Jarrow Formulas® SAMe 200 is a dietary supplement providing S-Adenosyl Methionine (SAMe) in tablet form, manufactured by Jarrow Formulas. Each tablet delivers 200 mg SAMe (net yield) derived from 400 mg of SAMe Tosylate Disulfate, and is foil blister-packed to maximize stability.
SAMe is a naturally occurring metabolite of methionine, an essential amino acid, and is found in all living cells. SAMe is a chiral molecule consisting of two forms: the biologically active (S,S) SAMe and the biologically inactive (R,S) SAMe. Jarrow Formulas® SAMe is produced by microbiological fermentation and then processed without chemical solvents to preserve 68–80% (S,S) SAMe.
SAMe supports balanced mood, joint health, and liver function. SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes, and SAMe has also been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood. SAMe supports the production of healthy connective tissue through transulfuration, a process in which glycosaminoglycans (GAGs) — including glucosamine and chondroitin — are sulfated by SAMe metabolites to yield sulfated GAGs such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage. SAMe also supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver function.
The tablets are manufactured under low temperature and low humidity conditions and feature EnteroGuard®, a proprietary cellulose-based, food-grade, pH-sensitive enteric coating. Each tablet is individually foil blister-packed. The product is Non-GMO, vegan, and gluten free.
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Tablet | ||
| Amount Per Serving | %DV | |
| S-Adenosyl Methionine (from 400 mg of SAMe Tosylate Disulfate) | 200 mg | † |
| † Daily Value (DV) not established. | ||
| Other Ingredients: Microcrystalline cellulose, mannitol, coating (hypromellose acetate succinate, stearic acid [vegetable source], triethyl citrate, riboflavin), glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide and sodium starch glycolate. | ||
| No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame. | ||
| Warning: Do not use if pregnant or nursing. Individuals with Parkinson's disease, bi-polar disorder, or manic depression should not use this product. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are under the age of 18, are taking medication (antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors) or have a medical condition; if adverse reactions occur, discontinue use. Keep out of the reach of children. Store in a cool, dry place. Do not use if safety seal or blister is broken, damaged or missing. | ||
S-Adenosyl Methionine (SAMe) — supports the synthesis of phosphatidylcholine and the formation or metabolism of neurotransmitters through methylation reactions, supports healthy connective tissue production through transulfuration, and supports the synthesis of glutathione (GSH) critical for antioxidant defenses and liver function.
